Will Eggs be a New Source of Cancer Drugs?

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Researchers in Japan have found a new way to produce cheaper drugs. They are using a staple food to treat a range of diseases. The ingredient is none other than chicken eggs. They have successfully modified hens to produce eggs containing large amounts of containing large amounts of interferon beta protein, a protein used to treat various illnesses, including multiple sclerosis and cancer.

The protein is very expensive and costs $300-$1000 for just one microgram. Using chicken eggs as a cure for cancer will reduce the price of cancer drugs by at least 90% if proven successful in further clinical trials. 

The scientists now have three hens laying daily, whose eggs contain the drug.

The conventional production of interferon needs large sterile facilities, but eggs work as a protein-producing aseptic system. 

A range of biological systems can be used to try and create drug, such as bacteria and yeast and some other mammalian cells. However, some proteins just don’t suit these systems.  

Interferon was discovered as a cell-signalling protein molecule in the body which acts against viruses. Later it was used to treat auto-immune diseases -- where a person's immune system attacks their body -- like multiple sclerosis. 

Interferon can also be manufactured from bacteria like insulin or from Chinese hamster ovary cells. The quantity of interferon produced this way, however, is very little.

Before chicken eggs, the Japanese scientists tried to produce the modified protein by inserting the required genes into chicken chromosomes using a virus as a vector, but said this produced an "irregular result. The new method seems to be more accurate and stably produces protein. 

With the use of modified chicken eggs to cure cancer, there is a kind of immediate hope for those battling cancer. This will definitely result in affordable medical products. Research is underway to produce human antibodies using the same method.

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